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Abstract

Vitamin B12 deficiency in infants often produces haematological and neurological deficits, including macrocytic anaemia ,neurodevelopmental delay or regression, irritability, weakness ,hypotonia , ataxia, apathy, tremor, and seizures. The diagnosis of vitamin B12 deficiency can be difficult when the typical macrocytic anaemia is absent ) Infantile vitamin B-12 deficiency with ineffective haematopoiesis and degeneration of nervous tissue has been reported in breast fed infants of mothers on strict vegetarian diets 2) ) Adults may tolerate vitamin B-12 deficient diets for many years without apparent symptoms due to their endogenous stores. In contrast, infants have very limited hepatic reserves of vitamin B-12 and so may develop symptoms of deficiency within month's 2) ( . we report two cases in which they were diagnosed as cerebral palsy in early life. first case was 9 month old female baby presented with pallor for last 3 months of age, floppiness ,regress of acquired millstone ,exclusive breast feed for a vegan mother ,diagnosed as megaloblastic anemia second case was 16 months old male baby presented with apathiness , he was exclusively breast feed till this age with minimum complementary food. KEY WORDS : megloblstic anemia ,breast feed

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