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Abstract

ABSTRACT: BACKGROUND: Pre-emptive analgesia is important for reduction of post operating pain in all surgical procedure including inguinal herniorraphy under, general anaesthesia. OBJECTIVE: To compare the effectiveness of pre-emptive analgesia for reduction of post-operative pain in inguinal herniorrhaphy under general anaesthesia. PATIENT AND METHOD: 30 adult ASA1 male patients undergoing inguinal herniorraphy under general anaesthesia were included in randomized prospective clinical study. The patients classified into two groups. Group 1 (n=15) control group receive 20 mg Ketamin Hcl at induction of anesthesia before operation. Group 2(n=15) receive 75 mg diclofenac sodium 30 min.I.M before induction and1 microgram/Kg Fentanyl citrate at induction of anesthesia. Then 20 ml of 0.25% Bupivacaine infiltrated in tissue under abdominal sheath at surgical area after induction of general anesthesia with another 20 ml of 0.25% Bupivacain was deposited in subfascial area after skin incision and. VAS (visual analog scale) score were all recorded. RESULT: In control group (group1) showed mark increase in stress response to post-operative pain as evidence by high visual analogue scale and in stress response to pain as increase in heart rate and mean arterial pressure during 1st 24hr post-operative. While group II patient (study group) mark decrease in post-operative pain as evidence by low VAS and insignificant change in heart rate and mean arterial blood pressure. It shows that pre-emptive analgesia reduces severity of post-operative pain and analgesic requirement in post-operative period. CONCLUSION: Our result indicates that pre-emptive analgesia is effective in reduction of post-operative period.

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