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Abstract

BACKGROUND: diabetic nephropathy is being recognized as a worldwide public problem with high cost and poor outcomes, there is increase in the incidence and prevalence of renal failure all over the world. Functional renal imaging methods such as diffusion- weighted magnetic resonance imaging (DWMRI), has been shown to be a promising technique in the evaluation of renal function OBJECTIVE: To study the value of apparent diffusion coefficient (ADC) in the detection and evaluation of diabetic nephropathy, correlating these values with the clinical stage of diabetic nephropathy and to compare these findings with diabetic patient without nephropathy. PAT IENTS AND METHODS: A cross sectional analytic study was conducted in MRI unit of Radiology department at Al-Imamein Al-Kadhimyain medical city through period form 1st oct.2017 to 30 of July 2018, 80 diabetic patients were classified according to GFR into two groups; group I 40 patients (diabetic patient with no nephropathy) group II 40 patients (diabetic patients with nephropathy). DWI ( b value ,0 and 1000 s/mm2) was performed in two group of the study . The mean ADC value of renal cortex was calculated from three regions positioned in the upper, mid and lower third of the kidney. The Relationship between ADC value and stage of diabetic nephropathy were assessed. RESULTS: In comparing diabetic patients (with no nephropathy) with patient with diabetic nephropathy, there was significant decline in mean ADC value among patients with advanced stages of diabetic nephropathy(p< 0.001). The mean ADC value with diabetic nephropathy was significantly lower among patients with type I DM (P

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