•  
  •  
 

Abstract

ABSTRACT: BACKGROUND: Fever occurs in about 80% of patients with hematologic malignancy during chemotherapy-induced neutropenia. Fever during chemotherapy-induced neutropenia may be the only indication of a severe underlying infection. OBJECTIVE: To determine the common types of bacterial pathogens causing febrile neutropenia and their susceptibility to antibiotics in patients with hematological malignancies in Baghdad Teaching Hospital. PATIENTS AND METHODS: 50 patients with hematological malignancies and febrile neutropenia were enrolled in this cross sectional study. All patients were sent for CBC, GUE, blood culture and sensitivity test. Other sample cultures were sent on indication RESULTS: AML (42%) was the most common malignancy .Blood culture was positive in (24%). The most common bacteria isolated by blood culture was Staphylococcal aureus (41.67%), gram positive bacteria were predominant in hematological malignancy (62.5%), positive sputum culture was obtained in 4(8%) of patients. The most frequently effective antibiotic was Imipenem for gram positive infections, and Amikacin, Imipenem and Piperacillin/Tazobactum for Gram negative infections. CONCLUSION: Gram positive bacteria were the most common bacteria with Staphylococcal aureus as the most common bacterial pathogen isolates in blood culture and streptococcal pneumonia in sputum culture, Imipenem was most commonly effective antibiotic.

Download

Share

COinS