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Abstract

BACKGROUND: The validation of the non-invasive radiological tools to replace invasive procedures like Endoscopic retrograde cholangiopancreatography (ERCP)for diagnosis of biliary obstructive disease become essential in modern medical practice. Magnetic resonance cholangiopancreatography (MRCP) is best alternative for ERCP regarding diagnostic aspects. AIM OF STUDY: To assess the diagnostic accuracy of MRCP and transabdominal US in identifying the cause of biliary dilatation in correlation with Endoscopic retrograde cholangiopancreatography as the gold standard. METHODS: A prospective cross sectional analytic study that involved 64 patients with obstructive jaundice. Abdominal US and MRCP were performed and the cause of obstruction were recorded and correlated with a subsequent ERCP results which were considered as the gold standard. Accuracy, sensitivity, specificity, positive and negative predictive values and P value were calculated for each test. RESULTS: Choledocholithiasis was the commonest cause of biliary obstruction (45%). The detection rate for MRCP was 96.6% and for ultrasound was 41.4% regarding CBD stones. The diagnostic performance of MRCP for malignant pathologies was (‌91.7%‌) sensitivity,100% specificity, 91.7% accuracy with significant level for detection (P value <0.001).While trans-abdominal ultrasound had lower diagnostic parameters for malignancy detection with 75% sensitivity, 66.7% specifity, 41.6% accuracy and P value (0.228). CONCLUSION: MRCP is a non-invasive technique that can detect level and cause of biliary obstruction with high diagnostic performance especially in choledocolithiasis and malignancies. MRCP can replace the invasive ERCP as a diagnostic tool in most cases. Also if no cause was identified in MRCP, ERCP can be avoided in most cases    

DOI

10.52573/ipmj.2021.174071

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