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Abstract

BACKGROUND: palmoplantar keratoderma (PPK) is an umbrella term for any form of persistent thickening of                     the epidermis at palmar and/or plantar surfaces, and includes hereditary and acquired conditions.  PPK can manifest clinically as diffuse, focal and punctate forms. OBJECTIVE: To study the frequency, clinical features and etiological correlation of hereditary and acquired PPK. PATIENTS AND METHODS: The study is observational, descriptive and cross-sectional. It was conducted at the Dermatology Center, Medical City, Baghdad Teaching Hospital, during the period from February 2019 to April 2020 patients with hereditary and acquired PPK were included in this study. Detailed history, clinical examinations and investigations when appropriate were done to reach the diagnosis. RESULTS: Two hundred and eighty patients with PPK were enrolled in this study; 138 (49.3%) were males and 142 (50.7%) were females. Patients were divided into 2 groups; group A (hereditary PPK) included 22 patients (8%) with mean±SD age of 17.63±13.46 years. Group B (acquired PPK) included 258 patients (92%) with mean ±SD age of 31± 20.43 years. Both palms and soles were more commonly affected than palms or soles alone. The most common morphological type was focal (51%) followed by diffuse in (47%). The most common diagnosis in group A was ichthyosis (7 patients, 31.81%), while the most common cause in group B was psoriasis (116 patients, 44.96%). Itching was the predominant symptom in both groups. PPK was seen among housewives, students and manual workers. Family history was positive in 12 (54.55%) patients in group A and 82 (32%) patients in group B. CONCLUSION: PPK is frequently encountered among Iraqi patients. Psoriasis was found to be the most common cause. Clinically the most common type was focal. Itching was the most common reported symptom.  

DOI

10.52573/ipmj.2021.174610

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