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Abstract

Background: Cavernous malformation is A well-circumscribed, benign vascular hamartoma consisting of irregular thick and thin-walled sinusoidal vascular channels located within the brain. lacking intervening neural parenchyma, large feeding arteries, or large draining veins. Usually 1–5 cm in size, may haemorrhage, calcify or thrombose, choosing best method of surgical treatment is crucial in order to decrease the cavernoma size, rate of haemorrhage and associated neurological symptoms.Methods: From Nov. 2021 to Dec. 2023 there were 40 cases of cavernous malformation treated by gamma knife radiosurgery at Dr. Saad Al-Witry Neuroscience Hospital by experienced neurosurgeon and approved for gamma knife radiosurgery all patients were followed up by clinical and radiological assessment. Results: The mean age was (39.5 ± 5) years; (60%) of patients were males. The most prevalent sites of cavernous malformation were cortical followed by brainstem. Pre gamma knife the most common size was 2-2.9 cm3 (42.5%), meanwhile post gamma knife the most common size was 1-1.9 cms3 in (35%), in addition to (5%) of the cavernomas disappear completely. By McNemar test there was significant association between Gamma knife radiosurgery and decreasing rate of haemorrhage, as well as decreasing in prevalence rate of reported seizure, hemiparesis, hemisensory loss and cranial nerves deficits. Conclusion: Gamma knife radiosurgery.

DOI

10.52573/ipmj.2025.156849

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