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Abstract

ABSTRACT: BACKGROUND: Human semen contains high concentrations of zinc (Zn) and copper (Cu) in bound and ionic forms .The presence of abnormal levels of these trace elements may affect spermatogenesis with regard to production , maturation , motility , and fertilizing capacity of the spermatozoa. The aim of this study is to evaluate the levels of Zn and Cu in seminal plasma in different groups of male infertility and to correlate their concentrations with various semen parameters. METHODS: Forty primary infertile male individuals ,who had regular unprotected intercourse for at least one year without conception with their partners ,aged 25-40 years were involved in the present study .After seminal plasma fluid analyses they were grouped as, azoospermic (n=12), oligoasthenozoospermic (n=16) ,and teratozoospermic (n=12) .Twelve fertile males selected from general population and after seminal fluid investigation were taken as normospermic control group .Zinc and Copper concentrations in separated seminal plasma of each infertile male and fertile control subject were determined by atomic absorption spectrophotometer. RESULTS: This study showed significant decrease of seminal plasma Zn mean (+SEM) value in oligoasthenozoospermic infertile males than in fertile male controls (p

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